Application Cases

Experiment Name: Dielectrophoresis-Based Microfluidic Droplet Sorting and Fusion Using Power Amplifiers

Research Direction: Microfluidics

Experimental Content:

1. Generate microdroplets using a microfluidic chip and perform droplet sorting via fluorescence excitation.

2. Achieve high-throughput fusion of two droplets through microfluidic chip manipulation.

Test Objective: Manipulate microdroplets using high-voltage, high-frequency electrical signals.

Test Equipment: Fluorescence microscope, microfluidic chip, laser, high-voltage amplifier, data acquisition card, high-speed camera, etc.

Experimental Procedure:

A fluorescence detection system was established by integrating the microfluidic chip with an optical setup. Using the ATA-2161 high-voltage amplifier, a 10 Vpp signal was amplified to over 1.5 kV to apply a dielectrophoretic force to the microdroplets. This caused droplet deflection or electro-coalescence, enabling high-throughput sorting and fusion of the microdroplets.

Experimental Results:

The high-frequency, high-voltage signal amplified by the ATA-2161 generated sufficient dielectrophoretic force on the microdroplets to induce deflection and electro-coalescence.

Figure: ATA-2161 High-Voltage Amplifier Specifications and Parameters